> For the complete documentation index, see [llms.txt](https://docs.bcbi.brown.edu/codiac-for-health/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://docs.bcbi.brown.edu/codiac-for-health/computing/python/large-language-models-llms.md).

# Large Language Models (LLMs)

More information to come!

## Overview

Unstructured clinical text accounts for over 80% of health data. Traditional natural language processing (NLP) methods lack contextual flexibility and domain generalization. Large Language Models (LLMs) enable advanced capabilities: summarization, classification, translation, reasoning.

## Ollama

Ollama is an open-source framework for managing, running, and serving large language models locally on host hardware.

### Prompt Engineering at Scale

* Standardizes prompt templates and variables
* Runs multiple prompts iteratively for evaluation or comparison
* Logs inputs/outputs for reproducibility and auditability

### Input

* Imports both structured data (like spreadsheets/CSVs) and standardized healthcare files (like FHIR patient records)
* Cleans and extracts raw narrative text from unstructured sources, such as messy clinical notes
* Clinical tables and free text can be combined in prompts.

### Output

* LLM responses parsed and stored programmatically.
* Results may be written to data frames or databases for downstream use.


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